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Jan. 31st, 2006 12:30 pm![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png){kind=small}
semperfionaI really dig the doctor I got at the Maternal-Fetal Health Center. He's got a great sense of humor.
"Well, you're not normal."
*chuckle* "I know that! In what respect am I abnormal today?"
It turns out that I have an abnormality of MTHFR (methylenetetrahydrofolate reductase) called the A1298C mutation. As a matter of fact, I have it on both genes; both of my parents therefore have at least one bad copy. All of the other likely causes of the thrombosis appear to have been ruled out. I do not have an acquired clotting disorder, and I do not have any of the other genetic abnormalities.
This enzyme is part of the processing of folic acid; the abnormality is associated with increased risk of heart disease and stroke (wonder if there's a relationship to the tachycardia I used to have?). Even when
not pregnant or trying to conceive he recommends I take a daily baby aspirin and a daily multivitamin with 400mcg of folic acid.
It is also highly associated with incidence of spina bifida and in later pregnancy with placental insufficiency; high doses of folic acid protect against both. From now until delivery, I am prescribed to take Folgard. Until conception (or say until March/April when we plan to start trying), I should take 1 Folgard every day plus a multivitamin (aiming for 2200-3000mcg folic acid per day) and then start taking two Folgard every day (5200mcg per day).
I'll have to start injections of Lovenox (low-molecular-weight heparin) at 6 wks gestation (must ensure the pregnancy is not ectopic before starting anticoagulants).
His last words to me: "Go get pregnant."
At some point I expect I'll want to have Rosa tested for this condition as well--she obviously has at least one bad copy of the gene--and I'm going to have to let my birth family know about it so they can take whatever precautions they feel necessary.
"Well, you're not normal."
*chuckle* "I know that! In what respect am I abnormal today?"
It turns out that I have an abnormality of MTHFR (methylenetetrahydrofolate reductase) called the A1298C mutation. As a matter of fact, I have it on both genes; both of my parents therefore have at least one bad copy. All of the other likely causes of the thrombosis appear to have been ruled out. I do not have an acquired clotting disorder, and I do not have any of the other genetic abnormalities.
This enzyme is part of the processing of folic acid; the abnormality is associated with increased risk of heart disease and stroke (wonder if there's a relationship to the tachycardia I used to have?). Even when
not pregnant or trying to conceive he recommends I take a daily baby aspirin and a daily multivitamin with 400mcg of folic acid.
It is also highly associated with incidence of spina bifida and in later pregnancy with placental insufficiency; high doses of folic acid protect against both. From now until delivery, I am prescribed to take Folgard. Until conception (or say until March/April when we plan to start trying), I should take 1 Folgard every day plus a multivitamin (aiming for 2200-3000mcg folic acid per day) and then start taking two Folgard every day (5200mcg per day).
I'll have to start injections of Lovenox (low-molecular-weight heparin) at 6 wks gestation (must ensure the pregnancy is not ectopic before starting anticoagulants).
His last words to me: "Go get pregnant."
At some point I expect I'll want to have Rosa tested for this condition as well--she obviously has at least one bad copy of the gene--and I'm going to have to let my birth family know about it so they can take whatever precautions they feel necessary.
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no subject
Date: 2006-01-31 07:00 pm (UTC)I love YOU! Start taking pills now, please.
*SQEE*
Date: 2006-01-31 09:26 pm (UTC)no subject
Date: 2006-02-01 06:25 pm (UTC)