Depressing phone call
Jan. 16th, 2007 02:01 pm![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png){kind=small}
semperfionaYesterday afternoon, while we were driving home from S. Missouri, I got
a phone call from Diane. She says the progesterone test I had last
Monday showed that no ovulation had occurred this month. I said, "But
what about the smiley face?!?!" She said she didn't know, maybe the
ovulation was later than we thought--in which case the IUI probably
missed it anyway. She wants to switch me to letrozole instead of clomid.
As far as I can tell letrozole isn't even approved for infertility
(yet?), although there are lots of people using it for that, with some
apparent success. It's a breast cancer drug, listed as "known to cause
birth defects if taken while pregnant" and therefore approved only for
use post-menopause. It works by suppressing aromatase, whatever that is,
and thereby preventing the release of estrogen. Or something.
But here it is, day 14, the day I was supposed to be able to take a
pregnancy test. My period has not yet started, but I don't feel very
optimistic.
a phone call from Diane. She says the progesterone test I had last
Monday showed that no ovulation had occurred this month. I said, "But
what about the smiley face?!?!" She said she didn't know, maybe the
ovulation was later than we thought--in which case the IUI probably
missed it anyway. She wants to switch me to letrozole instead of clomid.
As far as I can tell letrozole isn't even approved for infertility
(yet?), although there are lots of people using it for that, with some
apparent success. It's a breast cancer drug, listed as "known to cause
birth defects if taken while pregnant" and therefore approved only for
use post-menopause. It works by suppressing aromatase, whatever that is,
and thereby preventing the release of estrogen. Or something.
But here it is, day 14, the day I was supposed to be able to take a
pregnancy test. My period has not yet started, but I don't feel very
optimistic.
![[identity profile]](https://www.dreamwidth.org/img/silk/identity/openid.png){kind=small}
no subject
Date: 2007-01-16 08:51 pm (UTC)Still hoping for the best.
no subject
Date: 2007-01-16 09:20 pm (UTC)You only take it *during* your period, and it clears out of the system within ~45 hours, so the chance of it still hanging around during a prospective pregnancy is low.
Why does she think the Clomid isn't working?
Because there have been several other months with no indication of ovulation, despite the Clomid. Fewer, since I went to the higher dose, but the research I did today implies that raising the dosage again is unlikely to improve my odds. It does look like the letrozole works, and the stuff I read said no higher incidence of birth defects than otherwise.
no subject
Date: 2007-01-16 09:23 pm (UTC)no subject
Date: 2007-01-16 10:55 pm (UTC)no subject
Date: 2007-01-17 02:36 am (UTC)*thinking of you*